Werner Syndrome Affects 1 in 100,000
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A rare inherited condition that causes dramatic, early aging
87% Informative
Werner syndrome is caused by mutations in the WRN gene, which is needed to make the Werner protein.
Symptoms of the syndrome typically start to emerge in the second decade of life, around adolescence.
People with the syndrome are thin and have a slow growth rate later in childhood, sometimes missing the usual growth spurt.
Family members of people with Werner syndrome can undergo genetic counseling to see if they're carriers of mutant WRN genes.
Those who carry only one copy don't develop the syndrome but could pass on the condition to their children.
Couples who are carriers but still wish to conceive a child can potentially explore preimplantation genetic testing.
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