Ketamine, Dexmedetomidine Work Similarly
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Different anesthetics, same result: Unconsciousness by shifting brainwave phase

80% Informative
New study finds that an easily measurable brain wave shift of phase may be a universal marker of unconsciousness under general anesthesia .
Ketamine and dexmedetomidine work very differently, but in the operating room they do the same exact thing: anesthetize the patient.
When brain waves fall out of phase, local communications, and therefore functions, fall apart, producing unconsciousness.
The new results raise many opportunities for follow-up studies.
Does propofol (another anesthetic) also produce this signature of changed phase alignment? What role do traveling waves play in the phenomenon? And given that sleep is also characterized by increased power in slow wave frequencies, could phase alignment explain the difference?.
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