"Perturb-multiome Reverse Engineering"
This is a news story, published by ScienceDaily, that relates primarily to CRISPR news.
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Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells
81% Informative
Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation.
The method, called 'Perturb-multiome,' uses CRISPR to knock out the function of individual transcription factors across many blood cells at once.
The researchers then perform single-cell analyses on each cell to measure the effects of the editing, including identifying which genes have been turned on or off.
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