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Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

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Drug-delivering DNA aptamers target leukemia stem cells for one-two knockout punch.

Short snippets of DNA that can target molecules like larger antibodies do -- not only deliver cancer-fighting drugs, but also are themselves toxic to cancer stem cells.

Leukemia and other cancers of the blood are more difficult to target than cancers that produce localized tumors.

University of Illinois at Urbana-Champaign , Illinois , led by Abhisek Dwivedy , Dhyanesh Baskaran , Gaurav Sharma , Dhanush Gandavadi , Abhichart Krissanaprasit , Joonsu Han , Yusheng Liu , Zack Zimmers , Tshepo Mafokwane , Ichrak Hayah .

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