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Antibiotic-resistant bacteria is a serious public health threat.
Understanding the biology of these bacteria is essential for developing new strategies to counter antibiotic resistance.
Researchers at the Yong Loo Lin School of Medicine , National University of Singapore , have made progress in uncovering how Streptococcus pneumoniae constructs its capsule.
The ability to build a capsule that transports a wide range of sugar building blocks has potential applications in glycoengineering.
Understanding this process can help scientists develop new strategies for treating bacterial infections and explore ways to use these transport systems for engineering beneficial sugar-based materials.
Future research will focus on identifying specific amino acid residues responsible for transporter-substrate interactions and engineering transporters with optimised specificity for potential industrial and healthcare applications.
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