Peacekeeper Cells Prevent Autoimmunity
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Peacekeeper cells protect the body from autoimmunity during infection
76% Informative
Peacekeeper cells protect the body from autoimmunity during infection.
New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own.
Study provides a better understanding of immune regulation during infection and could provide a foundation for interventions to prevent or reverse autoimmune diseases.
Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection.
Instead of deleting all helper T cells reactive to self-antigens, you simply generate enough of these Treg peacekeeper cells instead.
"It's like flipping the idea of self-nonself discrimination upside down," says Savage.
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