H5N1 Influenza Evolution Risks

This is a Charlotte news story, published by MSN, that relates primarily to University of North Carolina news.

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H5N1 influenza virus

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H5 influenza variants

Medical Xpress - medical research advances and health news

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Science

H5N1 influenza viral lineages beginning to evade human immunological defenses, research finds

Summary

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91% Informative

H5N1 influenza virus is evolving to escape immunological defenses raised by previous infection or vaccination in mammals.

Researchers at University of North Carolina at Charlotte studied 1,804 viral protein-host antibody comparisons from 1996 to 2018 .

The study provides guidance for keeping pace with a rapidly adapting viral threat.

Avian influenza poses an ongoing threat to global agricultural interests.

Computational modeling results show worsening trend of antibody performance along with the already present animal pandemic is a cause for concern for an eventual human pandemic.

The authors write that high-performance computing provides rapid and reliable results to inform leaders in preparedness.

High-performance computational modeling is a pathway for "chipping away at multiple angles of biological variation at speed and scale".

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formal

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English

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