Immunotherapy Boosts Pancreatic Cancer Therapy
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Immunotherapy may boost KRAS-targeted therapy in pancreatic cancer

83% Informative
Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy.
Nearly 90 percent of pancreatic cancers are driven by KRAS mutations , the most common cancer-causing gene mutation across cancer types, which researchers long considered "undruggable" Patients with pancreatic cancer have an overall poor prognosis.
Vonderheide is an inventor on patents relating to cancer cellular immunotherapy and KRAS immune epitopes.
The study was supported by Revolution Medicines , the National Institutes of Health , the Department of Defense , the Molecular Pathology and Imaging Core , A Love for Life , the Basser Center for BRCA and the Penn Pancreatic Cancer Research Center .
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