Cancer Kill Switch Reactivated
This is a SungHee Park news story, published by ScienceDaily, that relates primarily to Mattia Brugiolo news.
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Scientists discover how to reactivate cancer's molecular 'kill switch'

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Researchers discover how to reactivate cancer's molecular 'kill switch' Discovery could open door to game-changing RNA -based multi-cancer treatments.
Researchers discover that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2.
Story Source: Journal Reference: - Nathan K. Leclair, Mattia Brugiolo , SungHee Park , Maeva Devoucoux , Laura Urbanski , Brittany L. Angarola , Marina Yurieva , Olga Anczuków . Antisense oligonucleotide-mediated TRA2 poison exon inclusion induces the expression of a lncRNA with anti-tumor effects. Nature Communications , 2025 ; 16 ( 1 ) DOI: 10.1038 /s41467-025-56913-8 Cite This Page:.
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