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Clinical trial tests novel stem-cell treatment for Parkinson's disease

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Summary
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84% Informative

Phase 1 clinical trial at Mass General Brigham examining safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem cells are reprogrammed to replace dopamine cells in the brain.

The clinical trial, based on more than three decades of research, has treated three-of-six participants who will be tracked for more than a year .

The autologous transplantation approach circumvents the requirement for immunosuppressive treatments.

The Phase 1 open-label clinical trial will be the first such trial to test blood-derived autologous iPSC-derived dopamine neurons in patients with Parkinson's disease.

The study was supported by a NINDS CREATE Bio grant ( U01NS109463 ).

VR Score

88

Informative language

93

Neutral language

28

Article tone

formal

Language

English

Language complexity

78

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not offensive

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not hateful

Attention-grabbing headline

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Known propaganda techniques

not detected

Time-value

long-living

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1

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1

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