Microbubbles Deliver Targeted Drugs

This is a news story, published by Phys Org, that relates primarily to ETH Zurich news.

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microbubble interaction

Phys Org

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Science

Ultrasound-activated microbubbles form high-speed jets for drug delivery

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87% Informative

ETH Zurich researchers have investigated how tiny gas bubbles can deliver drugs into cells in a targeted manner using ultrasound.

For the first time, they have visualized how tiny cyclic microjets liquid jets generated by microbubbles penetrate the cell membrane, enabling the drug uptake.

Microbubbles are smaller than a red blood cell, are filled with gas and have a special coating of fat molecules to stabilize them.

The right combination of frequency, pressure and microbubble size can help to maximize the outcome of the therapy.

Just a few pulses of ultrasound are enough to perforate a cell membrane.

Conversely, the coating of the microbubbles can also be optimized for the required ultrasound frequency, making it easier for the jets to form.

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English

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