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bladder preservationScienceDaily
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Radiation plus combination immunotherapy may help preserve bladder in some patients with muscle-invasive bladder cancer.
The standard of care for localized MIBC is radical cystectomy, the removal of the entire bladder.
Radiation plus the immune checkpoint inhibitors (ICIs) durvalumab and tremelimumab had durable responses that allowed for bladder preservation.
Bladder Preservation with Durvalumab plus Tremelimumab and Concurrent Radiotherapy in Patients with Localized Muscle-Invasive Bladder Cancer (IMMUNOPRESERVE): A Phase II Spanish Oncology GenitoUrinary Group Trial. Clinical Cancer Research, 2025 ; 31 ( 4 ): 659 DOI: 10.1158/1078-0432.CCR-24-2636 Cite This Page:.
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