acetylcholinesterase prevents paralysis
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Designing enzymesThe Conversation
•Science
Science
Enzymes are the engines of life − machine learning tools could help scientists design new ones to tackle disease and climate change
82% Informative
Scientists have spent decades trying to design their own enzymes to make new molecules, materials or therapeutics.
Enzymes are proteins large molecules that do the behind-the-scenes work that keep all living things alive.
For an enzyme to function, it adopts a shape that perfectly matches the molecule it processes.
The active site of the enzyme precisely orients amino acids to interact with the target molecule when it enters.
This makes it easier for the molecule to undergo a chemical reaction to turn into a different one, making the process go faster.
Recent advances in deep learning have dramatically changed the landscape of designing enzymes with computers.
Sam Pellock : Enzymes can now be generated in much the same way that AI models such as ChatGPT and DALL-E generate text or images.
He says the resulting enzymes from these efforts performed much more slowly than those found in nature.
VR Score
80
Informative language
78
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47
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