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The Jerusalem Post

The Jerusalem Post

Health

Health

TAU makes breakthrough in drug delivery to treat inflammatory bowel disease

The Jerusalem Post
Summary
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74% Informative

Tel Aviv University researchers have successfully delivered mRNA-based drugs to the intestine without passing through the liver.

This groundbreaking development could make possible effective treatments for chronic and incurable inflammatory diseases such as Crohn ’s disease and ulcerative colitis.

About seven million people around the world and 15% of the US population suffer from inflammatory bowel disease (IBD).

Lipid-based drugs are encased in synthetic lipid nanoparticles that mimic biological membranes.

In vaccines, such as the COVID-19 vaccine, the mRNA is encapsulated in lipid particles containing about 10% of phospholipid.

The researchers increased the ratio to 30% causing the particles to float through the bloodstream like oil on water.

VR Score

70

Informative language

68

Neutral language

47

Article tone

informal

Language

English

Language complexity

61

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possibly offensive

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not hateful

Attention-grabbing headline

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Known propaganda techniques

not detected

Time-value

long-living

Source diversity

1

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