Genetic Signature Aids Cancer Treatment

This is a angiosarcoma news story, published by MSN, that relates primarily to University of Florida news.

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vascular cancers

Study Finds

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Science

Dogs with deadly cancer help scientists crack code of rare human disease

Summary

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86% Informative

Study led by University of Florida researchers demonstrates how specific genetic mutations strengthen immune system responses in angiosarcoma , an aggressive cancer that affects blood vessels.

By examining both human and canine cases, researchers uncovered crucial mechanisms that could help develop more effective treatments for this rare but devastating disease.

The study identified potential weaknesses in how these mutated cancer cells respond to a specific drug.

The research team employed CRISPR/Cas9 gene editing technology to create cells with specific PIK3CA mutations.

This sophisticated approach allowed them to study exactly how these mutations affect cancer cell behavior.

Researchers identified specific cell populations that were resistant to drug treatment, providing valuable insights into potential treatment strategies.

The findings may also have implications for other cancers with similar mutations.

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semi-formal

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English

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