KCNB2 Gene Blockers Malignant Brain Tumors
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childhood brain cancerScienceDaily
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Science
Targeting potassium channel shows promise for treating brain tumors
79% Informative
Researchers find blocking the KCNB2 gene can slow tumor growth, paving the way for next-gen treatments for childhood brain cancer.
Potassium channels play a crucial role in helping tumour-propagating cells multiply to drive medulloblastoma growth.
The discovery opens the door to developing new therapies that could transform how we treat this common childhood brain tumour.
A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance.
Developmental Cell , 2025 ; DOI: 10.1016/ j.devcel.2025.001 Cite this article as part of a study by the U.S. Department of Medicine .
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