Endocan Targets Glioblastoma Signaling
This is a endokan news story, published by EurekAlert!, that relates primarily to Brain Cancer news.
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Science
Tumor-secreted protein may hold the key to better treatments for deadly brain tumor, study finds
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UCLA scientists have found targeting a protein called endocan and its related signaling pathway could be a promising new approach for treating glioblastoma, an aggressive and lethal brain cancer.
The team of researchers discovered that endokan , which is produced by endothelial cells lining blood vessels in the tumor, drives tumor growth and makes the cancer resistant to standard therapies such as radiation.
The work was supported in part by grants from the National Institutes of Health , the UCLA SPORE in Brain Cancer and the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation. Journal Nature Communications .
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