Human norovirus replication hubs discovered
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norovirus replicatesScienceDaily
•Researchers discover replication hubs for human norovirus
80% Informative
Researchers at Baylor College of Medicine and the University of Texas , MD Anderson Cancer Center report in Science Advances .
The findings could lead to designing antiviral drugs to prevent, control or treat these serious infections.
Human norovirus is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year.
The RNA polymerases of almost all norovirus strains have a high propensity to form these replication factories, suggesting that this may be a common phenomenon of most noroviruses.
"This is a remarkable paper, and I was glad we could validate the findings in virus-infected cells using our human intestinal enteroids cultivation system".
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