brittle star's pliability control

This is a news story, published by Phys Org, that relates primarily to Jacob Machado news.

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brittle star genomics

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tissue engineering

Phys Org

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Unlocking the secrets of collagen: How sea creature superpowers are inspiring smart biomaterials for human health

Summary

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Major findings on inner workings of a brittle star's ability to reversibly control the pliability of its tissues will help researchers solve the puzzle of mutable collagenous tissue (MCT) MCT modulator genes are the specific molecular instructions determining emergent tissue modifications.

This advanced research to pinpoint relevant molecular processes in an echinoderm could eventually open new doors for regenerative therapies.

Unlike humans or mice, brittle stars present unique barriers to research because they are considered "non-model organisms" The research team has outlined significant pathways for future exploration using ISH and RNAi to identify and zero in on the genes that control MCT .

Jacob Machado is hopeful genetic targeting will be the catalyst for a prototype to drive future transformative human biomedical applications.

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