ALPHA-003: Dementia Drug Breakthrough
This is a news story, published by New Atlas, that relates primarily to Filamon news.
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tau neurofibrillary tanglesNew Atlas
•'Breakthrough' dementia drug looks to stop disease in its tracks
75% Informative
ALPHA-003 is designed to preserve the integrity of vital brain cell structures and protect them against destruction caused by brain inflammation.
In healthy neurons, the tau protein stabilizes microtubules, crucial tube-like structures that, together with neurofilaments, maintain the neurons’ shape and provide mechanical support.
When it’s modified, tau can form toxic aggregates tangles that degrade these key structures.
It’s expected that the drug will treat tauopathies other than the two major forms of dementia Alzheimer’s disease and frontotemporal dementia such as progressive supranuclear palsy, an uncommon Parkinson’s-like disorder, and CTE , caused by repeated concussions. Source: Filamon [ PDF ].
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