SnoRNAs Enhance Gene Regulation
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RNA targetsPhys Org
•New technique points to unexpected uses for snoRNA across many cell types
88% Informative
Small nucleolar RNAs (snoRNAs) guide RNA molecules that steer chemical modifications to cellular ribosomal RNA (rRNA) targets.
University of Chicago researchers uncovered thousands of previously unknown targets for snoRNAs.
Some of the newly discovered interactions with messenger RNA (mRNA) facilitate protein secretion, an important cellular process.
The paper is a showcase of collaboration between the Biological Sciences Division and Physical Sciences Division at UChicago.
"This paper is another example that this kind of collaboration leads to opening a new field of biology," says UChicago researcher.
"SnoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification".
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