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autism spectrum disorderMedical Xpress - medical research advances and health news
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88% Informative
Tel Aviv University study expands understanding of biological mechanism underlying genetically-based autism.
Mutations in the SHANK3 gene are responsible for nearly one million cases of autism worldwide.
Researchers applied a genetic treatment that improved the function of cells affected by the mutation.
The study was published in the journal Science Advances .
These findings have important implications, both clinical and scientific.
They identify the mechanism causing the damage to myelin .
This finding offers hope for developing genetic treatment for humans, which could improve the myelin production process in the brain.
Inbar Fischer: Recognizing the significance of myelin impairment in autism opens new pathways for understanding the brain mechanisms underlying autism.
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