Membraneless Organisms Transform Biology
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many additional membraneless organellesLive Science
•Rogue 'organs' inside cells may hold secrets of the origin of life on Earth
77% Informative
Membrane-bound organelles were the textbook standard of how scientists thought cells were organized until they realized in the mid-2000s that some organs don't need to be wrapped in a membrane.
Biomolecular condensates are breaking some long-held beliefs about protein chemistry.
They create a new microenvironment that attracts additional proteins and RNA molecules, thus forming a unique compartment within cells.
Allan Albig : Evidence that individual nucleotides can spontaneously assemble into chains to make RNA .
He says this is a crucial step in the RNA world hypothesis, which postulates that the first "lifeforms" on Earth were strands of RNAs.
Condensates are already changing how we think about human diseases like Alzheimer's, Huntington 's and Lou Gehrig's , he says.
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