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Scientists discover chemical probes for previously 'undruggable' cancer target

Phys Org
Summary
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77% Informative

Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1) FOXA1 mutations can enable these types of cancers to grow and proliferate.

The team's findings also mapped out how tiny drug-like chemical compounds—called small molecules—interact with the protein.

Sang Joon Won, Yuxiang Zhang , Christopher J. Reinhardt , Lauren M. Hargis , Nicole S. MacRae , Kristen E. DeMeester and Jarrett R. Remsberg of The Scripps Research Institute are the authors of the study.

VR Score

88

Informative language

94

Neutral language

46

Article tone

formal

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English

Language complexity

54

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not offensive

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not hateful

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Known propaganda techniques

not detected

Time-value

long-living

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