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alternative lineage genesScienceDaily
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79% Informative
Researchers from the School of Veterinary Medicine and Perelman School of Medicine have found that YY1 knockout pro-B cells can generate T lineage cells helping B cells produce antibodies.
"The data has come out better than my wildest fantasy," says senior author Michael Atchison .
The mountain of data the team amassed "can be mined for a long time to look at what's happening when you knock out YY1," Atchison says.
Another avenue of research would be to see how well knockout works in other cell types and tissues.
This work was supported by the National Institutes of Health and an Aspire award from the Mark Foundation for Cancer Research .
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