GTPases Target Drug Discovery

This is a Cell news story, published by MSN, that relates primarily to GTPase news.

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drug discovery

Phys Org

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Scientists learn how to drug wily class of disease-causing enzymes

Summary

Nutrition label

85% Informative

GTPases are involved in a myriad of diseases from Parkinson's to cancer.

Because of their slippery exteriors, they have remained largely out of reach of modern drug discovery, with the exception of the notorious cancer-causing GTPase called K-Ras .

The approach revealed new drug binding sites that could not have been predicted by computational drug discovery tools.

The findings, published on Sept. 9 in Cell , create a long-awaited opportunity to develop therapies for the many, diverse diseases.

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English

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