Ozempic, Wegovy Gain Popularity
This is a U.S. news story, published by Gizmodo, that relates primarily to Wegovy news.
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diabetes drug OzempicGizmodo
•How Ozempic Worksâand Whatâs Still a Mystery
74% Informative
The active ingredient in Novo Nordisk’s Ozempic and Wegovy is semaglutide, which belongs to a group of drugs known as GLP-1RAs .
GLP is one of several hormones that play a key role in regulating our metabolism and hunger.
Natural GLP1 doesn’t last very long in our body, with a half -life of only minutes .
Lab-made proteins have been developed that can activate the same receptors that GLP 1 does, while lasting much longer in our system.
SemagLutide in particular boasts a week , well above the 13 or so hours for exenatide.
GLP-1RAs are one especially potent lever that we can use to address the biological underpinnings of obesity, if not the only one available.
In large-scale clinical trials, people taking Wegovy were shown to lose around 15% of their body weight over a year.
GLP-1RAs do appear to be safe and effective for the majority of patients taking them.
The adult obesity rate in the U.S. is currently around 42% , and the prevalence of obesity has continued to rise in many states even since the approval of Wegovy in 2021 .
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