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How Ozempic Worksâand Whatâs Still a Mystery

Gizmodo
Summary
Nutrition label

74% Informative

The active ingredient in Novo Nordisk’s Ozempic and Wegovy is semaglutide, which belongs to a group of drugs known as GLP-1RAs .

GLP is one of several hormones that play a key role in regulating our metabolism and hunger.

Natural GLP1 doesn’t last very long in our body, with a half -life of only minutes .

Lab-made proteins have been developed that can activate the same receptors that GLP 1 does, while lasting much longer in our system.

SemagLutide in particular boasts a week , well above the 13 or so hours for exenatide.

GLP-1RAs are one especially potent lever that we can use to address the biological underpinnings of obesity, if not the only one available.

In large-scale clinical trials, people taking Wegovy were shown to lose around 15% of their body weight over a year.

GLP-1RAs do appear to be safe and effective for the majority of patients taking them.

The adult obesity rate in the U.S. is currently around 42% , and the prevalence of obesity has continued to rise in many states even since the approval of Wegovy in 2021 .

VR Score

62

Informative language

55

Neutral language

30

Article tone

informal

Language

English

Language complexity

55

Offensive language

possibly offensive

Hate speech

not hateful

Attention-grabbing headline

not detected

Known propaganda techniques

not detected

Time-value

long-living

External references

20

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