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harmful gene changesScienceDaily
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77% Informative
New research identifies specific genetic changes that can increase a person's risk of breast and ovarian cancers, to help guide clinical decision-making.
Researchers from the Wellcome Sanger Institute and their collaborators focused on the 'cancer protection' gene RAD51C.
The study also identified regions of the protein essential for its function pointing to new roles in cancer development and potential therapeutic targets.
New data will be highly useful for diagnostic laboratories to better understand the RAD51C gene changes that we identify on clinical genetic testing in cancer patients and their family members.
Professor Clare Turnbull , clinical lead of the study, said: "These new data will help us to conclude which gene changes are harmful and which are innocent".
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