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menopause managementScience News
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84% Informative
Two phase 3 clinical trials compared the drug elinzanetant with a placebo at two timepoints.
The drug subdued hot flashes quickly: By the fourth week , a majority of those taking the drug reported at least a 50 percent reduction in frequency.
By the 12-week mark, more than 70 percent of those who took the drug experienced a drop in hot flash frequency.
Participants on the drug also reported significantly improved sleep compared with those on placebo.
There is a 52-week trial of elinzanetant assessing longer-term safety.
Another trial is looking at how well the drug works for women receiving therapy for hormone-positive breast cancer.
Many women experiencing hot flashes and other bothersome symptoms of menopause are n’t getting sufficient or appropriate treatment.
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