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understanding smellNature
•
76% Informative
The chemical structure of a molecule tells you almost nothing about its odour.
Two chemicals with very similar structures can smell wildly different.
Two wildly different chemical structures can produce an almost identical odour. And most smells — coffee, Camembert , ripe tomatoes — are mixtures of many tens or hundreds of aroma molecules.
AI algorithm did well at predicting the smell of compounds compared with the average group assessments.
It performed better than the typical individual sniffer.
The map it produced was very complicated — it has more than 250 dimensions.
It was able to group smells by type, such as meaty , alcoholic or woody.
Structure of one OR ca n’t tell us much, says Hiro Matsunami , an olfaction biologist at Duke University in Durham , North Carolina .
Different odorants probably engage a single OR in distinct ways, he says.
Machines are using machine learning to accelerate the search for structures and their preferred chemical partners.
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