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Nature

Nature

Gender-affirming therapy reshapes the immune systems of trans men

Nature
Summary
Nutrition label

81% Informative

Study is one of the largest yet to examine how gender-affirming hormone therapy ( GAHT ) affects the immune system over time.

It could explain why men tend to be more susceptible to viral infections than women and women are often more prone to autoimmune conditions.

The study is important because physicians want GAHT “to be safe, of course”.

Transmasculine person (assigned female at birth but identifying with masculinity) has autoimmune condition called Sjögren ’s syndrome.

Jamie has traded testosterone therapy for an immunosuppressant called adalimumab (sold as Humira ) in an effort to improve their health.

VR Score

87

Informative language

90

Neutral language

59

Article tone

informal

Language

English

Language complexity

63

Offensive language

likely offensive

Hate speech

not hateful

Attention-grabbing headline

not detected

Known propaganda techniques

not detected

Time-value

long-living

Source diversity

1

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