Blood clots affect brain, body
This is a COVID-19 news story, published by ScienceDaily, that relates primarily to Akassoglou news.
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blood coagulationScienceDaily
•Discovery of how blood clots harm brain and body in COVID-19 points to new therapy
75% Informative
Study overturns prevailing theory that blood clotting is merely a consequence of inflammation in COVID-19 .
Blood coagulation protein fibrin causes unusual clotting and inflammation that have become hallmarks of the disease.
Fibrin also suppresses the body's "natural killer" cells, which normally clear the virus from the body.
Fibrin that leaks into the brain triggers neurologic diseases, such as Alzheimer's disease.
In COVID-infected mice, fibrin is responsible for harmful activation of microglia, brain's immune cells.
Akassoglou 's lab previously developed a drug, a therapeutic monoclonal antibody.
Researchers: Fibrin drives thromboinflammation and neuropathology in COVID-19 .
The study was published in the journal Nature 's " Nature " journal, which has published more than 1,000 articles in the past 10 years .
The authors are currently working on a novel book called " Fibrin-drive-19 ".
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