Mitochondria Linked to Early Death

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mitochondrial DNA insertions

ScienceDaily

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Mitochondria are flinging their DNA into our brain cells

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77% Informative

Mitochondria live inside all our cells, but unlike other organelles, mitochondria have their own DNA, a small circular strand with about three dozen genes.

Mitochondrial DNA is a remnant from the organelle's forebears: ancient bacteria that settled inside our single-celled ancestors about 1.5 billion years ago .

Those with more mitochondrial DNA insertions in their brain cells were more likely to die earlier than those with fewer insertions.

Researchers looked at a population of human skin cells that can be cultured and aged in a dish over several months .

When the cells' mitochondria were dysfunctional from stress, the cells accumulated NUMTs four to five times more rapidly.

"This shows a new way by which stress can affect the biology of our cells," says Weichen Zhou .

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