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liver transplantWired
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83% Informative
Using messenger RNA , the same technology used in some of the Covid-19 vaccines, scientists hope to reprogram terminally ill organs to be fit and functioning again.
The team plans to begin a clinical trial next year to test the idea in people with end-stage liver disease.
Livers are the second most in-demand organ in the US .
The Pitt team is using mRNA to essentially turn back time in injured organs.
mRNA is a molecule that carries instructions for making proteins, including transcription factors.
HNF4 alpha seems to act like a main control panel, regulating much of the gene expression in liver cells.
The team is gathering data from the rat and human liver experiments to submit a clinical trial application to the FDA .
VR Score
83
Informative language
83
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51
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informal
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English
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48
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possibly offensive
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long-living
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