Kamala Harris and Nancy Pelosi: How America's most powerful women look to make history again

Vice President Kamala Harris is aiming to become the nation’s first female president in 2021 .

Both are products of the San Francisco Bay area's Democratic political machine.

Pelosi and Harris aren't close personally, but their unlikely rise through San Francisco's competitive political environment instilled in them a mutual admiration.

Pelosi said she was particularly impressed by how quickly Harris wrapped up the presidential nomination.

San Francisco is a good training ground for politicians with ambitions for state or national office.

It's one of the most competitive political environments in the country, officer seekers must learn to navigate an electorate that is diverse, passionate and actively involved in the political process.

To maneuver through San Francisco politics requires unique coalition building, political operative Alex Tourk says.

Kamala Harris is the first Black woman and the first Asian woman to lead a presidential ticket.

If she wins the presidency, she will shatter another glass ceiling.

Pelosi is a tactician while Harris is better at putting herself in other people’s shoes, Etienne said.