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mast cell functionScienceDaily
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75% Informative
Researchers at the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the University of Münster have discovered a hidden talent of mast cells: they can capture and use another type of immune cell called neutrophils.
This surprising discovery sheds new light on how our immune system works, particularly during allergic reactions.
Mast cells release leukotriene B4 , a substance commonly used by neutrophil to initiate their own swarming behavior.
By secreting this substance, mast cells engulf into a vacuole cell-cell structure that the researchers refer to as "mast cell structure".
New understanding of how mast cells and neutrophils work together adds a whole new layer to our knowledge of allergic reactions and inflammation.
Mast cells can release the newly acquired neutrophil components in a delayed manner, triggering additional immune responses.
Researchers have already begun investigating this interaction in mast cell-mediated inflammatory diseases in humans.
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