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eastern equine encephalitis virusScienceDaily
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78% Informative
New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death.
The findings offer important lessons in virology that may help guide better preparedness for future outbreaks of other viral diseases.
The most recent outbreak in the United States in humans was in 1987 , according to Centers for Disease Prevention .
Harvard researchers say WEEV "submerged" as a human pathogen in North America .
The researchers say subtle shifts in the shape of the viral spike proteins changed the cellular receptors with which the virus could connect.
This change in targetable host receptors is likely the central reason why the virus re-emerged.
The findings serve as an important reminder that viruses are part of a dynamic system.
So Yoen Choi , Isaac M. Chiu , Vesna Brusic , Paula Montero Llopis , Joshua M. Boeckers , and Hisashi Umemori from Harvard Medical School .
This work was supported by Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease Awards .
VR Score
89
Informative language
96
Neutral language
48
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English
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