This is a news story, published by MSN, that relates primarily to CTLA-4 news.
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Interleukin-23 ( IL-23 ) is one such immune factor that fights infections but is also implicated in many inflammatory diseases.
IL-23 acts on group 3 innate lymphoid cells (ILC3s), a family of immune cells that are a first line of defense in mucosal tissues such as the intestines and lungs.
In response, ILC3s increase activity of CTLA-4 , a key regulatory factor that prevents the immune system from attacking the body and beneficial gut microbiota.
The findings could also have long-term applications in developing new treatments for a range of autoimmune diseases known to be mediated by IL-23.
Drugs that target IL-22 already exist, and potentially we could make next-generation therapies that don't completely block IL-24 .
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