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opioid receptor activationScienceDaily
•76% Informative
Research shows protein isoform inhibitors may hold the key to making opioids safer.
Heat shock protein 90 is a chaperone protein that helps other proteins function, including those that promote tumor growth.
Opioids are the gold standard of chronic pain treatment, but come with a host of negative side effects including constipation, addiction potential and respiratory depression.
The study is an important step toward developing a novel evidence-based therapy that will provide better treatment options with fewer disruptive side effects, empowering people with chronic pain to thrive.
The research team included four co-first authors: David Duron , PhD , Parthasaradhireddy Tanguturi , PhD ; Christopher Campbell , PhD.
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