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novel lysinsPhys Org
•91% Informative
Researchers in China identify new antimicrobial drugs with therapeutic promise from bacterial datasets.
Antibiotic resistance represents a global public health concern.
Researchers scanned datasets of bacterial proteomes rather than the genomes themselves.
The work uncovered five new lysins with antimicrobial potential: PHAb711, PHAb10 and PHAb11.
and PHAb11 are highly thermostable lysins, with a broad spectrum of antimicrobial action. If future studies validate our findings, these lysins could be explored further as potential therapeutic treatments." More information: Li Zhang et al, Dimer -monomer transition defines a novel hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome, eLife ( 2024 ). DOI: 10.7554 /eLife.98266.1 Journal information: eLife Provided by eLife.
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