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tamoxifenGuardian
•76% Informative
British-American pharmacologist Craig Jordan , who has died aged 76 , was the first to show that tamoxifen could stop tumours growing by blocking the female hormone oestrogen from locking on to cells in the breast.
He made his discoveries in the face of huge scepticism from the medical community.
He was not a medical doctor but a laboratory scientist who conducted his research on rats and mice.
Craig Jordan discovered tamoxifen could be used to prevent cancer coming back after surgery.
He also discovered a very effective breakdown product that went on to form the basis of other drugs that prevent postmenopausal women from losing bone density.
In 1980 he moved permanently to the US , where he held senior positions at a succession of leading research universities.
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