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SMIM1 gene variantNews
•86% Informative
People with a genetic variant that disables the SMIM1 gene have higher body weight because they expend less energy when at rest.
One in 5,000 people lack both copies of the gene, making them Vel -negative.
This group is also more likely to be overweight, a conclusion which could one day lead to new treatments.
The team hopes to test whether a cheaply and widely available drug for thyroid dysfunction may be effective in treating obesity in people who lack the gene.
VR Score
88
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88
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75
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English
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63
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long-living
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3
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