This is a news story, published by Nature, that relates primarily to Ec news.
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unmodified prostate cancer cellsNature
•76% Informative
Ec peptide (PEc) is associated with prostate cancer progression by inducing proliferation, metastases, and tumour repair.
An anti-PEc monoclonal antibody ( MAb ) was developed to examine the effects of this antibody on prostate cancer and its possible side effects.
The study was conducted with respect to cellular proliferation, migration, invasion, toxicity to tumours and effects on the cell cycle.
IGF-IEc expression is associated with advanced clinical and pathological stage of prostate cancer.
IL-6 is associated to IGF-1Ec upregulation and Ec peptide secretion, from prostate tumours.
IGF-I/IIneutralizing antibody MEDI-573 potently inhibits IGF signaling and tumour growth.
Expression of insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage.
Increased expression of IGF-1Ec with increasing colonic polyp dysplasia and colorectal cancer.
IGF-IEc expression is linked to advanced differentiated thyroid cancer.
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