Family History Affects Alzheimer's Risk

This is a news story, published by Mass General Brigham | Integrated Health Care System, that relates primarily to M. et al news.

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Asymptomatic Alzheimer

Mass General Brigham | Integrated Health Care System

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Maternal Inheritance of Alzheimer’s Disease Tied to Increased Risk of Developing Disease

Summary

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90% Informative

A new study by investigators from Mass General Brigham suggests that whether a person inherits risk of Alzheimer’s disease from their mother or father influences risk of biological changes in the brain that lead to disease.

The study examined 4,400 cognitively unimpaired adults ages 65-85 .

Researchers observed that having only a paternal history of late-onset memory impairment was not associated.

This work was funded by the United States National Institutes of Health (K23AG062750, R01AG063689 U19AG010483 , and DP2AG082342). The A4 Study is funded by NIH grants, Eli Lilly and Co , and several philanthropic organizations. Paper cited: Seto, M. et al . “Parental history of memory impairment is associated with -amyloid in cognitively unimpaired elderly” JAMA Neurology. DOI: 10.1001 /jamaneurol.2024.1763.

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Informative language

Neutral language

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formal

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English

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not offensive

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not hateful