Oocytes Protect DNA from Damage
This is a news story, published by Quanta Magazine, that relates primarily to Böke news.
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oocytesQuanta Magazine
•Researchers discover how mouse oocytes keep DNA safe from damaging proteins
79% Informative
Researchers discover how mouse oocytes keep DNA safe from damaging proteins.
The cells construct special compartments within themselves to temporarily sequester proteins.
Then, heeding a molecular signal, the storage units disperse all at once, practically vanishing along with their dangerous cargo.
The work reveals a new way that oocytes quietly work to preserve genetic quality.
Oocytes store misfolded proteins and then wipe them out all at once.
Neurons destroy their cellular detritus throughout their life spans, while oocytes store them.
Böke ’s lab is collaborating with fertility clinics to look at protein aggregates in human oocytes.
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