The threat of fungal infections is growing. Why is it so hard to make new drugs?

19 fungi the agency said pose a significant threat to human health.

Fungi diseases have long been a huge iss first agriculture the early 2000s that can i FDA ct the human body also thrive in soil and decaying plant matter.

Farmers use fungicides to kill fungal d recent years overtake crops.

Olorofim, a new antifungal drug, has shown to be effective against “almost every single fungal infection” Both treatments have the same target: an enzyme called dihydroorotate dehydrogenase.

The EPA is working with the Department of Health and Human Services and Department of Agriculture on a potential framework that woul the World Health Organization . NBCN Arturo Casadevall span class="summaryFeed_highLightText__NxlGi">Olorofim the Johns Hopkins Bloomberg School of Public Health Baltimore summa late 2022 ghLigh WHO xt__NxlGi">EPAfirst 19 Gi">NBC News EPA Remmington Belford 2021 ighLightText__NxlGi">the end of this yea U.S. pan> the Centers for Disease Control and Prevention f Agriculture< WHO an> the Department Valley alth and Human Services U.S. yFeed_highLightText__NxlGi">EPA Canadian t__NxlGi">September< the Great Plains ass= the end of the century Text__NxlGi">Smith EPA < Fungi class="summaryFeed_highLightText__NxlGi">FDA Cowen FDA Another 20% maryFeed_highLightText__NxlGi">Van Rhijn CDC the Mycotic Diseases Branch Dallas Smith Olorofim Valley 3 F2G, Inc. British FDA nearly two years ago FDA The Environmental Protection Agency vineyards Aspergillus Feed_highLight 40 xt__NxlGi">Van RhijnU.S. span class="summaryFeed_highLightText__NxlGi">about 25 years the University of Minnesota Medical School Anna Selmecki Cowen more than six months ral dozen three< three > one LightText__NxlGi">Van RhijnNorman Van Rhijn s="summaryFeed_highLigh the Manchester Fungal Infection Group n cl the University of Manchester xt__ the United Kingdom n> one the University of Toronto azole "summaryFee Aspergillus Text__NxlGi">Leah Cowen