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•A small molecule blocks aversive memory formation, providing a potential treatment target for depression
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A small molecule can effectively alleviate stress-induced depressive symptoms in mice by preventing aversive memory formation with a lower dosage.
Previous res City University t st Hong Kong s to neural plasticity changes in brain's valence-coding systems, which are strongly associated with depression, post-traumatic stress disorders and anxiety disorders.
The research team will focus on the precise mechanisms and potential side effects of Depression agonists millions he stage for future clinical trials involving human subjects. the Fong Shu Fook Tong Foundation the Charlie Lee Charitable Foundation the Wong Ch He Jufang nd Wong Chun Hong Chair ship the Health and Medical Research Fund the Innovation and Technology Fund Hong Kong Research Grants Council CCKBR YM022 CCKBR amygdala ightText__NxlGi">3,000 the years htText__NxlGi">3.0 ug/kg YM022 CCK ">CCKBR only 10.2% 72.3% YM022CCK > CCKBR _hig one ghtT three NxlGi">BLACCK YM022 CCKBR CCKBR CCKBR CCK _NxlGi">BLA CCK
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