Todd Sacktor's Childhood Memory

This is a Crick news story, published by Wired, that relates primarily to Francis Crick news.

Crick news

For more Crick news, you can click here:

more Crick news

Francis Crick news

For more Francis Crick news, you can click here:

more Francis Crick news

biology news

For more biology news, you can click here:

more biology news

Wired news

For more news from Wired, you can click here:

more news from Wired

About the Otherweb

Otherweb, Inc is a public benefit corporation, dedicated to improving the quality of news people consume. We are non-partisan, junk-free, and ad-free. We use artificial intelligence (AI) to remove junk from your news feed, and allow you to select the best science news, business news, entertainment news, and much more. If you like biology news, you might also like this article about

neuron store memories

. We are dedicated to bringing you the highest-quality news, junk-free and ad-free, about your favorite topics. Please come every day to read the latest fleeting childhood moment news, memory formation news, biology news, and other high-quality news about any topic that interests you. We are working hard to create the best news aggregator on the web, and to put you in control of your news feed - whether you choose to read the latest news through our website, our news app, or our daily newsletter - all free!

help memories

Wired

•

Science

How the Binding of Two Brain Molecules Creates Memories That Last a Lifetime

Summary

Nutrition label

84% Informative

Todd Sacktor studies molecules involved in maintaining the neuronal connections underlying memory.

How the essence of a lived moment is encoded and retrieved remains one of the central unanswered questions in neuroscience.

In 1984 , Francis Crick described a biological conundrum: Memories last years , while most molecules degrade in days or weeks .

Sacktor became a neuroscientist in pursuit of an answer.

Researchers have found that an interaction between two proteins is key to keeping memory intact over time.

They found that in the absence of PKM , mice recruit a backup mechanism, involving another molecule, to strengthen synapses.

They developed a new molecule to inhibit the activity of the protein, but it wasn’t clear how.

The KIBRA and PKM proteins stabilize each other by forming a bond.

That way, when a protein degrades and needs to be replaced, the other remains in place.

The discovery addresses the conundrum first identified by Crick , namely how memories persist despite the relatively short lifetimes of all biological molecules.

VR Score

Informative language

Neutral language

Article tone

informal

Language

English

Language complexity

Offensive language

not offensive

Hate speech

not hateful