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other coronavirusesScienceDaily
•Health
Health
78% Informative
A promising path to fighting COVID and other coronaviruses may have been based on a serious mistake.
Scientists had zeroed in on a part of the virus called the NiRAN domain, believed to be a powerful target for new antiviral drugs.
But when a Rockefeller team revisited a highly cited 2022 study, they found the evidence didn't hold up.
Discovery could help prevent wasted time and resources in the race to develop better treatments.
Rockefeller researchers published their findings in Cell .
They found key molecules that Yan and colleagues claimed to have seen simply were not there.
Placement of these molecules in the original model violated basic rules of chemistry, they say.
Even advanced methods designed to pick out rare particles turned up empty.
"Efforts based on a flawed structural model could result in years of wasted time and resources".
VR Score
90
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96
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56
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semi-formal
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English
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56
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long-living
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