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Sweet-smelling molecule halts therapy-resistant pancreatic cancer

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76% Informative

Japanese researchers found that benzaldehyde can stop the shape-shifting ability of aggressive cancer cells, which lets them dodge treatments and spread.

By targeting a specific protein interaction essential for cancer survival, benzaldehyde and its derivatives could form the basis of powerful new therapies, especially when combined with existing radiation or targeted treatments.

Benzaldehyde suppresses epithelial-mesenchymal plasticity and overcomes treatment resistance in cancer by targeting the interaction of 14-3-3ζ ; with H3S28ph.

The study was published in the British Journal of Cancer , 2025 .

VR Score

83

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88

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39

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formal

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English

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80

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long-living

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